High-potency, pure single-strain and multi-strain functional probiotic powders customized for global manufacturers.
Exploring the molecular biology and clinical efficacy profiles of advanced synbiotic ingredients.
The human gastrointestinal tract contains trillions of microorganisms. Clinical research indicates that physiological benefits of probiotics are highly strain-specific. For instance, Lactobacillus acidophilus plays an active role in mucosal barrier enforcement, while Lacticaseibacillus rhamnosus is widely documented for its immunomodulatory pathways. By utilizing targeted genetic identification, we provide single strains with highly defined metabolic profiles.
Prebiotics act as non-digestible dietary fibers that selectively stimulate the growth and activity of beneficial gut bacteria. When formulating synbiotics (the combination of probiotics and prebiotics), the structural architecture of prebiotic ingredients like Inulin, FOS, and XOS must be matched to the fermentative preferences of the selected strains. This synergy dramatically enhances colonization rates in the intestinal epithelium.
One of the primary challenges in probiotic formulation is ensuring survivability during manufacturing, storage, and gastric transit. Spore-forming strains such as Bacillus laterosporus and Bacillus licheniformis possess natural proteinaceous protective coats, making them exceptionally resistant to heat, high shear forces, and acidic gastric environments. These strains are ideal for functional foods and feed additives.
A premier global high-tech developer and manufacturer of functional nutrition and natural ingredients.
Shaanxi Diaries Biotech Co., Ltd. is a modern high-tech enterprise specializing in the research and development, production, and global distribution of plant extracts, natural raw materials, and functional ingredients for the health, food, and cosmetic industries.
With strong technical expertise and advanced manufacturing capabilities, the company is committed to providing high-quality, safe, and effective natural solutions to customers worldwide. Our products are widely used in dietary supplements, functional foods and beverages, cosmetics, personal care products, animal nutrition, and agricultural applications.
Over the years, Shaanxi Diaries Biotech has built long-term partnerships with more than 5,000 companies across over 80 countries and regions, earning a strong reputation for reliability, consistency, and innovation in the natural ingredients industry.
We also provide professional OEM/ODM services, including formulation support, product development, and private label manufacturing to meet diverse market needs.
Located in the historic biotech hub of Xi'an, Shaanxi Province, China, our manufacturing site covers more than 70,000 square meters. Operating under strict international GMP standards, the facility supports six state-of-the-art plant extraction and bio-fermentation lines.
Traceable, standardized manufacturing frameworks verified by international food safety bodies.
Shaanxi Diaries Biotech maintains a rigorous quality management system that meets demanding international standards. Our quality inspection and testing centers are equipped with HPLC, GC, UV, and atomic absorption spectrometers to monitor product purity, biological stability, and active CFU concentration.
Translating bacterial viability and matrix structures into vertical market opportunities.
Ensuring stability in dairy and liquid products requires advanced stabilization. We supply food-grade, freeze-dried powders that integrate cleanly into yogurts, ambient-stable functional drinks, and effervescent delivery systems. Our strains like Lactobacillus rhamnosus are optimized to resist process moisture and temperature fluctuations.
For encapsulation and tablet compression, we provide customized premixes with up to 150 Billion CFU/g potency. Our patented 5-Layer Micro-Encapsulation Technology shields delicate cells from gastric fluid, oxygen, and compression force, ensuring optimal targeted delivery to the gut tract.
Improving feed conversion efficiency and maintaining water quality are critical for commercial livestock and aquaculture operations. Our stable spore-formers like Bacillus laterosporus inhibit pathogenic Vibrio in shrimp aquaculture, acting as natural growth promoters and biocontrol agents.
Navigating the next generation of microbiomics: postbiotics, precision delivery, and clinical validation.
Development and scaling of lipid-protein shell coatings to guarantee shelf-stability of delicate lactic acid bacteria at ambient temperatures (25°C) without cold-chain infrastructure dependencies.
Pioneering cell-free supernatants and heat-killed probiotic fractions (postbiotics) that offer high thermodynamic stability in harsh cosmetic formulations and acidic beverages while retaining immune-boosting activities.
Establishing strain-level profiling matched to specific population metabotypes. Providing custom bioreactor outputs that match localized physiological deficiencies across global markets.
How Shaanxi Diaries Biotech ensures uninterrupted raw material pipelines for international brands.
We offer end-to-end custom formulation, blending, and tableting capabilities. Whether you require premium single strains in bulk quantities or complete private-label formulas packaged in hard capsules, sachets, or effervescent tablets, our facility is equipped to handle rapid scale-ups.
To ensure zero loss of bio-activity, our logistics system utilizes temperature-controlled packaging solutions. Real-time logging of thermal data ensures that when probiotics arrive at your manufacturing site, their CFU count matches the certificate of analysis.
Navigating Customs, FDA import alerts, and local food security declarations is complex. We provide comprehensive documentation support including full BSE/TSE statements, Allergen declaration checklists, Non-GMO certificates, and comprehensive third-party heavy metals reports.
Answering vital technical and logistical questions for procurement directors and product developers.
Standard freeze-dried powder contains active probiotic cells preserved at low temperatures, suitable for products with strict cold storage. Microencapsulated probiotic powder uses a protective multi-layer lipid or protein matrix coating around the bacteria. This shield prevents cellular damage from stomach acid, environmental humidity, and processing pressures, extending shelf stability at ambient room temperatures.
Spore-forming bacteria such as Bacillus licheniformis and Bacillus laterosporus are highly heat resistant. Because they form natural endospores, they can survive extreme conditions such as feed pelleting, extrusion, and high-heat cooking. For standard lactic acid bacteria, specialized microencapsulation formulations must be utilized to prevent thermal inactivation.
Yes. Shaanxi Diaries Biotech provides complete custom services. We can blend multiple probiotic strains (e.g., combining 13 strains for digestive balance), adjust total CFU counts per gram, incorporate prebiotic fibers like Inulin or FOS, and manufacture the final product in bulk powder, capsules, tablets, or single-serving sachets under your private label.
We provide a comprehensive batch-specific Certificate of Analysis (COA), including quantitative HPLC/microbial plates, heavy metals analysis, and pesticide residue verification. In addition, we furnish MSDS, Allergen declarations, Non-GMO verification statements, and documents supporting ISO, HACCP, Halal, Kosher, and USDA Organic certifications.
We utilize specialized insulated shipping containers with gel ice packs or dry ice systems. For high-volume air and sea shipments, we implement real-time temperature tracking tags, ensuring that the cold chain is strictly maintained from our manufacturing facility in Xi'an to your destination warehouse.
Explore our technical-grade dietary supplements, feed-grade cultures, and sleep-support formulations.
Diaries Biotech
